Biotin and derivatives
Medchemexpress LLC Biotin-PEG8-acid | 2143964-62-7 | 99.8% | C29H53N3O12S | 50 MG
Biotin-PEG8-acid is a biotin-labeled, PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker: one for an E3 ubiquitin ligase and the other for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. It is for research use only.
- Appears as a white to off-white solid
- Molecular weight: 667.81
Medchemexpress LLC Cancer antigen 125 (MUC16), recombinant human, biotinylated | >95.0% | 50UG
Recombinant human CA125 (MUC16) is a biotinylated protein fragment (~685 amino acids) produced in HEK293 cells with C-terminal His and Avi tags. It is intended for binding studies, assay development, and detection workflows that use biotin-streptavidin capture.
- Biotinylated for streptavidin-based capture and detection.
- Expressed in HEK293 cells to provide mammalian glycosylation.
- C-terminal His and Avi tags for purification and site-specific biotinylation.
- Supplied at laboratory quantity suitable for assay development.
- High purity as determined by reducing SDS-PAGE (>95%).
- Molecular weight range 90-140 kDa reflecting glycosylated forms.
Medchemexpress LLC Interleukin 23 | >90.0% | 20UG
Recombinant human interleukin-23 (heterodimer of p19 and p40), biotinylated and produced in HEK293 cells. Supplied as a 0.2 μm filtered PBS solution, this protein is designed for research into IL-23 receptor binding, JAK/STAT signaling, and Th17-related immune responses. Handle and store according to supplier recommendations to maintain activity.
- Human IL-23 heterodimer (p19 + p40).
- Biotinylated for affinity-based detection and capture.
- Expressed in HEK293 mammalian cells for native glycosylation.
- Contains C-terminal His and Avi tags to facilitate purification and immobilization.
- Purity >90% as determined by reducing SDS-PAGE.
- Predicted molecular weight ~55.8 kDa.
- Supplied in PBS, 0.2 μm filtered; avoid repeated freeze-thaw cycles.
Medchemexpress LLC SPDP-C6-NHS ester | 158913-22-5 | 98.1% | 425.52 g/mol | C18H23N3O5S2 | 250MG
SPDP-C6-NHS ester is an NHS-activated, cleavable linker that contains a disulfide bond and is used for bioconjugation and PROTAC synthesis. The reagent couples to primary amines via its NHS ester and enables reversible linkage through disulfide reduction. It is supplied as a powder with specified storage and stability conditions and is intended for research use only.
- Cleavable disulfide linker for reversible conjugation
- NHS ester reactive toward primary amines
- Suitable for PROTAC synthesis and bioconjugation applications
- High purity (98.1% as listed)
- Available in multiple pack sizes, including 250 mg
- Powder storage recommendations: -20°C for long term, 4°C for shorter term
Medchemexpress LLC Biotin-VAD-FMK | 1135688-15-1 | ≥98.0% | 672.81 | C30H49FN6O8S | 25 MG
Biotin-VAD-FMK is a cell-permeable, irreversible biotin-labeled caspase inhibitor used to detect and label active caspases in cell lysates. The biotin tag enables affinity capture for pull-down assays and biochemical profiling of active caspases.
TARGETMOL CHEMICALS INC DSPE-NHS 25MG
Also available in 5 mg, 10 mg, 50 mg, 100 mg and bulk. Please contact Fisher for quotes. DSPE-NHS is a lipid that is often combined with other compounds to form nanoemulsions that can be used in skin care products and pharmaceuticals. Purity 99.85%
Medchemexpress LLC Aeide-C1-NHS ester | 824426-32-6 | 98.0% | C6H6N4O4 | 25 MG
Aeide-C1-NHS ester is an alkyl/ether-based PROTAC linker used in the synthesis of PROTACs. It is also a click chemistry reagent, containing an Azide group. It can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups, and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Alkyl/ether-based PROTAC linker
- Used in PROTAC synthesis
- Click chemistry reagent
- Contains an Azide group
- Undergoes CuAAc reaction
- Undergoes SPAAC reactions
Medchemexpress LLC Azido-PEG24-NHS ester | 2375600-46-5 | 95.0% | C55H104N4O28 | 25 MG
Azido-PEG24-NHS ester is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, containing an Azide group that can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups.
- PEG-based PROTAC linker
- Utilized in the synthesis of PROTACs
- Functions as a click chemistry reagent
- Contains an Azide group
- Can participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules
- Can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules possessing DBCO or BCN groups
Cell Signaling Technology Goat Anti-Mouse IgG1 Antibody
Goat Anti-Mouse IgG1 Antibody (Biotin Conjugate) 1 mg
